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Agnirva Space Premier League - Expedition #31803: OREOcube: Probing the Effects of Space on Organic Molecules

OREOcube (ORganics Exposure in Orbit) is a European Space Agency experiment that investigates how organic compounds—specifically those relevant to astrobiology and planetary science—react when exposed to space conditions. With Principal Investigator Dr. Andreas Elsaesser and a consortium of space research entities including Kayser Italia, OHB SE, and the DLR Institute of Aerospace Medicine, the experiment was designed to simulate how organic molecules endure the harsh conditions of low-Earth orbit.


The International Space Station (ISS), orbiting around 400 km above the Earth, offers a unique laboratory to simulate extraterrestrial environments without leaving Earth’s gravitational influence. OREOcube makes full use of this advantage. Installed outside the ISS, the experiment exposed multiple organic molecules to direct space radiation, vacuum, and temperature extremes, closely mimicking environments like those on Mars or in deep space.


Understanding how these compounds degrade or transform has profound implications for planetary protection, space mission planning, and theories about the origin of life. For example, if certain amino acids or DNA bases break down rapidly in space, they would be less likely to survive long journeys to Earth on meteorites—a key hypothesis in panspermia.


The experiment used a robust hardware system to measure optical changes in these compounds during exposure. These measurements were then compared to ground-based controls to isolate space-specific effects. OREOcube also contributes to our knowledge of how spacecraft materials may change over time, helping engineers design better shielding and longer-lasting components.


OREOcube’s innovative design as a compact cube that fits into a standard space exposure platform makes it a model for future experiments in astrobiology. Its success on Expedition 69 shows how targeted, well-coordinated international collaborations can drive high-impact science.


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