Agnirva Space Premier League - Expedition #32636: Keeping Bones Strong in Space: New Imaging Models to Predict Spinal Injury

Long-duration spaceflight takes a toll on the human body, and one of the most concerning risks is spinal deterioration. The Quantitative CT and MRI-based Modeling Assessment project, led by Ashley Weaver and supported by NASA, is a deep-dive into the effects of microgravity on vertebral strength and the associated injury risk. Through expeditions 55/56 to 64, this study used advanced imaging to monitor changes in the spine before and after spaceflight.

The researchers used quantitative computed tomography (CT) and magnetic resonance imaging (MRI) to construct models that simulate the biomechanics of spinal loading. This allowed them to predict how much stress astronauts’ vertebrae could endure—and how that changes over time in microgravity.

By identifying structural weaknesses and potential injury points, these models guide personalized exercise routines, equipment choices, and recovery plans. The findings are crucial for planning longer missions to Mars and beyond, ensuring astronaut health and performance.

Join the Agnirva Space Internship Program to learn about biomechanics, human health in space, and medical imaging technology.

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